|
KMID : 0352819940100010019
|
|
Kosin Medical Journal
1994 Volume.10 No. 1 p.19 ~ p.28
|
|
|
Aclinical Study on Clinically Suspected Herpes Simplex Encephalitis
|
|
|
|
|
Abstract
|
|
|
Clinical features, electroencephalographic(EEC) findings, brain Computed Tomography(CT), Magnetic Resonance Imagings(MRI) and Single Photon Emission Computed Tomography(SPECT) findings were observed in 10 patients who were diagnosed as clinically
suspected herpes simplex encephalitis at Kosin Medical College Hospital and Ulsan Dongkang Hospital between July 1990 and June 1994
@ES The results were summarized as follows:
1) The mean age at onset was 28±9.75 year old. The ratio of male to female was 4 : 1.
2) The onset of illness was most common during the month of fall time.
3) majority of patients showed mental change, fever, and seizure.
4) In most cases, initial CSF findings showed lymphocytic plecocytosis with elevated protein level.
5) EEG findings were diffuse slowing in 100% and periodic lateralized epileptiform discharges(PLEDs) in 25%.
6) Brain CT showed localized temporal lobe low-density lesion and diffuse brain swelling. Brain MRI showed increased signal intensity in temporal lobe on t2-weighted images. Srain SPECT showed focal hypoperfusion and hyperperfusion.
7) 7) Acyclovir therapy was tried for 9 patients. 7 patients showed clinical improvement and 2 patients died.
8) As the sequelae, mental retardation and seizure were common.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|